Modafinil is a multipurpose drug.
It is a prescription medicine meant to treat narcolepsy and obstructive sleep apnea, but it also has a variety of “off-label” applications. Modafinil has gained popularity as an ADHD therapy during the last decade. Is modafinil useful for treating ADHD? How does it work?
What is ADHD?
ADHD is characterized by symptoms such as difficulties paying attention, impulsive conduct, and hyperactivity. It’s a frequent ailment in youngsters that can occasionally last into adulthood. According to one research, around 6% of children have ADHD. This ailment is multifaceted, and many variables may contribute to it.
ADHD has a significant hereditary component. A family or genetic link may be easily found in 75–91 percent of instances of ADHD. A new study analyzed the genes of persons with ADHD to examine dopamine activity.
Why Is This a Significant Finding for ADHD Patients?
What we can conclude from this research is that ADHD is linked to dopamine. This implies that when it comes to treating the ailment, we may try to address the concerns produced by gene variants. This study explains why medicines that improve ADHD the greatest also tend to increase dopamine levels. This comprises Adderall, Ritalin, Concerta, and Modafinil.
Modafinil for ADHD
Although modafinil is occasionally used by doctors to treat ADHD, it is considered “off-label” in the United States since the FDA has not yet authorized it for this use.
Modafinil and Dopamine
Modafinil has been demonstrated to boost dopamine concentrations in the brain . It works in a similar fashion to other prevalent ADHD drugs like as Ritalin and Adderall, both of which have a long history of usage in traditional medicine for treating ADHD.
Dopamine and Addiction
Unfortunately, the dopamine-regulated reward system is also in charge of the mechanisms involved in addiction. Because of their calming or pain-relieving properties, many illegal substances activate the reward system. As part of the reward, the brain releases oxytocin. After a while, the mind begins to seek the things that generate this oxytocin production, and we become hooked to the drug. These similar mechanisms can lead to addiction to exercise, sex, or food.
ADHD and the Reward Center
Most persons have sufficient dopamine levels and can successfully activate the reward center. This makes it easier to form routines and stay concentrated on the same activity for longer periods of time. People with ADHD struggle with this system and must work extra hard to receive positive input in the reward region of the brain. Concentrating on one work for more than a few minutes might be challenging since the brain seeks out more engaging things. If dopamine levels rise, we may be able to reduce the threshold for activation of the reward center. This would assist to reduce the fidgeting and jitteriness that is common in ADHD patients.
Stimulants for Overstimulation
It may appear unusual that a stimulant may be used to cure overstimulation. However, there is a completely acceptable explanation for this. Because persons with ADHD have a difficult time triggering the reward response in the brain, they self-stimulate by fidgeting or moving about. Modafinil raises dopamine concentrations in synapses by preventing neurons from reabsorbing and breaking it down. Dopamine is normally released to have its impact, then quickly reabsorbed and broken down. Modafinil inhibits reabsorption and breakdown, allowing it to exert its effects for LONGER lengths of time. Dopamine is critical for the brain’s ability to focus on one thing at a time. Dopamine is implicated in the brain’s reward center. The reward center is a distinct part of the brain that promotes the production of “feel good” chemicals such as oxytocin to reward useful activities. This is how habits are created. Our brain adores being rewarded and will seek out activities that elicit this response.
Where Can I Buy Modafinil?
There are several online modafinil vendors. Few of them, however, are of high quality. Many are imposter websites out to steal your credit card or Bitcoin payments. We have a lot of experience with them and have always found them to be a dependable and reasonable source of modafinil and armodafinil. Of course, there are other alternative sources for modafinil, both online and in-store. Just keep in mind that many of them require you to have a valid prescription in order to purchase.
ADD vs. ADHD
ADD and ADHD are closely related and are frequently used interchangeably. The presence of hyperactivity distinguishes the two. Some persons with attention deficit disorder (ADD) are hyperactive (fidgeting, frequent movements, inability to sit still), while others are placid. The diagnosis of ADD or ADHD is determined by whether or not hyperactivity is evident. Although the therapy for both is approximately the same, ADHD frequently needs particular medicines directed at the hyperactive aspect of the disorder.
How to Use Modafinil for ADHD
It is straightforward to use Modafinil for ADHD. Adults use doses of 100 mg or 200 mg to alleviate the symptoms of ADD or ADHD. Modafinil can be used for this condition in two ways:
1. Daily Use
This is the most usual dosage regimen for ADHD patients. A daily dosage of 100–400 mg modafinil can be used to alleviate symptoms and improve focus. The issue with this is the development of tolerance. When a medicine is used often over an extended period of time, the body often begins to develop resistance to its effects. This implies that more modafinil will be required to generate the same benefits as before. If you intend to use modafinil on a daily basis, it is suggested that you first discuss your situation and the choices available with your doctor. After checking with your doctor, we recommend purchasing modafinil online from a generic drug source such as MXL. This will be the most cost-effective and easy technique accessible, both with and without a prescription.
2. Regular Use
Some persons with ADHD prefer to use modafinil as needed. They’d have some on hand for days when they know they need to be productive, such as at school, work, or at home preparing for an exam. The benefits of using modafinil on a regular basis (1–4 times per week) include a lower risk of building tolerance to the medicine.
What Does Modafinil Feel Like?
Modafinil has the sensation of a strong cup of coffee. It isn’t as physically stimulating as previous ADHD drugs like Adderall or Ritalin, but it does generate strong sensations of excitement in the brain. When studying or working, it becomes much simpler to stay concentrated on the task at hand. You no longer have the strong want to get up and go someplace else, or to open Facebook and become engrossed in memes and images of your friend’s recent vacation to Bali.
How Long Does Modafinil Last?
Modafinil’s effects vary greatly from person to person, depending on their size, whether or not they ate a meal, and the quantity of the dose. Most people will begin to experience the benefits of modafinil approximately an hour after administration. For the following three hours, the effects progressively grow and reach a climax. The medicine gradually wears off over the following 7–14 hours. A 200 mg modafinil pill has a half-life of 12–15 hours. It can linger for up to 20 hours in rare circumstances.
What are the Drawbacks of Modafinil for ADHD?
Modafinil may induce anxiety or sleeplessness in certain people. Although this is a typical problem that can generally be prevented by taking modafinil earlier in the day, some people can’t seem to avoid it. If you have regular anxiety or sleeplessness while using modafinil, consider taking a week off (a day or two) or lowering your dose. Most folks see an improvement when they take their medication earlier in the day. If your anxiety or sleeplessness persists, it may be time to seek other treatment.
Other Factors to Consider When Treating ADHD
ADHD is highly linked to dopamine issues, but there are other aspects to consider. Diet has also been proven to play a crucial impact in the development of ADHD. According to nutritional study, persons with ADHD should avoid meals that are heavy in refined carbs and sugars, as well as salt, added food colors and coloring agents. Potential allergies should also be explored and avoided.